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Statement by ResMed on Plans to Renew Its Patent Infringement Case Against Fisher & Paykel

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SAN DIEGO /PRNewswire/ — ResMed today issued the following statement from David Pendarvis, the company’s global general counsel and chief administrative officer:

Experience the interactive Multimedia News Release here: https://www.multivu.com/players/English/74629527-resmed-patent-infringement-case-against-fisher-paykel/

“ResMed filed a motion to dismiss the current International Trade Commission (ITC) complaint so that we can refile and incorporate additional evidence generated since the original complaint was filed. We believe this will make our strong case even stronger, and we remain confident in our position in the ITC. ResMed’s innovations have transformed the treatment of sleep-disordered breathing. We’re committed to protecting our innovation, which is why we’ve engaged in global legal proceedings with Fisher & Paykel.”

About ResMed
ResMed (NYSE: RMD) changes lives with award-winning medical devices and cloud-based software applications that better diagnose, treat and manage sleep apnea, chronic obstructive pulmonary disease (COPD) and other chronic diseases. ResMed is a global leader in connected care, with more than 3 million patients remotely monitored every day. Our 5,000-strong team is committed to creating the world’s best tech-driven medical device company – improving quality of life, reducing the impact of chronic disease, and saving healthcare costs in more than 100 countries.­­ ResMed.com | Facebook | Twitter | LinkedIn

For media:

For investors:

Alison Graves

Agnes Lee

858-836-6789

858-836-5971

news@resmed.com

investorrelations@resmed.com

Logo – http://photos.prnewswire.com/prnh/20140310/LA79234LOGO-a

Source: ResMed
Related stocks: NYSE:RMD OTC-PINK:RSMDF

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May 19, 2017 at 3:13 pm

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L’Oréal Paris Celebrates 20 Years of Cinema & Beauty in Cannes

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PARIS /PRNewswire/ —

As the 70th Cannes Film Festival opens, L’Oréal Paris marks its 20th year as official beauty partner.

L’Oréal Paris begins its festival-long celebration of beauty and cinema with the Cannes public, starting today on the L’Oréal Paris beach.

Marking its second decade as the Official Cannes beauty partner, today L’Oréal Paris inaugurates its free Outdoor Cinema open to the public to celebrate women in film with six of its ambassador actresses. The brand opens its Pop-up Boutique to all festival-goers; and gives the world the first red carpet beauty looks under the new creative direction of global makeup director Val Garland. This edition also welcomes the new L’Oréal Paris Global spokesperson, the young andaccomplished actress Elle Fanning, who makes her debut on the red carpet on May 17th.

As Cannes enters its second week, the brand celebrates 20 years of collaboration with the Cannes Film Festival, its Canniversary, with the L’Oréal Cinéma Club soirée.

Cannes 2017, it’s going to be a beauty!

DAY BY DAY: BEAUTY AT THE FESTIVAL: L’OREAL PARIS AT CANNES 2017

May 17th -22nd Celebrating Beauty and Cinema: L’Oréal Paris Lights up the Big Screen with the L’Oréal Paris Outdoor Cinema open to the general public, Martinez beach.

From the opening night with Julianne Moore on the evening of May 17th, every evening has a different L’Oréal Paris actress. This includes new global ambassador Elle Fanning who will introduce her iconic film choices to the public, until May 22nd. These special free screenings start at 9pm every night.

May 17th Julianne Moore introduces Maps to the Stars, 2014, Award for Best Actress: 1h,52 minutes.
May 18th Susan Sarandon introduces Thelma and Louise, 1991, Out of Competition: 2h,10 minutes.
May 19th In her first role for the brand, Elle Fanning, new L’Oréal Paris actress ambassador, introduces Ginger & Rosa: 1h,30 minutes.
May 20th Aishwarya Rai introduces Devdas, 2002, Out of Competition: 3h,5 minutes.
May 21st Andie MacDowell presents Sex, Lies, and Videotape, 1989, Palme d’Or: 1h,40 minutes.
May 22nd Eva Longoria presents Lowriders, 2017, screening at the L’Oréal Paris Cinema following its worldwide release May 12th: 1h,39 minutes.

Democratizing the Festival experience to the public, the L’Oréal Paris Big Screen will show films at the same time as the official gala screenings, just along from the Palais des Festivals on the Martinez beach. Follow our social media channels to stay tuned for the latest updates.

MAY 17TH – 28TH: L’ORÉAL PARIS 100% MAKEUP CANNES POP UP BOUTIQUE

The first immersive L’Oréal Paris Pop-up Boutique is now open! Open every day of the festival, 100% dedicated to makeup, festival-goers can discover the beauty influences and innovations in real-time. Including the new red carpet looks created by new global makeup director Val Garland, the maverick artist behind some of the most inventive looks in beauty today and at Cannes for the first time in her new role at L’Oréal Paris. Revolutionizing the shopping experience, shoppers can access free tutorials, expert advice and services with a chance to win the exclusive and elusive, Cannes red carpet tickets! The boutique will also give fans and consumers the opportunity to discover the latest collection of products, including the limited-edition Red Carpet Color Riche, featuring the Palme d’Or – a collector’s edition created for the brand’s Canniversary. There is also the opportunity to have red carpet looks recreated by our makeup artists and to meet our actress ambassadors’ in-store.

MAY 24TH: THE CANNIVERSARY PARTY, L’ORÉAL PARIS CINEMA CLUB

Two decades calls for a celebration! On May 24th, L’Oréal Paris throws its biggest Cannes party yet, with the greatest names in filmmaking and beauty in attendance. A night where cinema comes to life, and different scenography, projections and installations celebrate the art of filmmaking. This all comes together with a live showcase and exclusive performance, watched by every L’Oréal Paris actress in town. Guests will include Eva Longoria, Bianca Balti, Barbara Palvin, Doutzen Kroes, Lara Stone, Maria Borges, Irina Shayk, Kristina Bazan, Alexina Graham, Neelam Gill and Léna Meyer Landrut along with Marlon Teixeira; and fashions designer, Olivier Rousteing.

MAY 25TH: AMFAR CINEMA AGAINST AIDS: GOLDEN AGE OF HOLLYWOOD COLLECTION

L’Oréal Paris hair and makeup artists bring beauty into the Golden Age of Hollywood by showcasing these styles on 40 top models including L’Oreal Paris ambassadors who will take to the charity runway at the Hotel du Cap-Eden Roc. This year’s list includes at the most sought-after faces on the Cannes schedule, including L’Oréal Paris ambassadors Doutzen Kroes, Bianca Balti, Barbara Palvin, Irina Shayk, Lara Stone, Maria Borges, Alexina Graham, Kristina Bazan, Neelam Gill and Marlon Teixeira among amfAR’s co-chairs. The event will bring together stars in film and fashion in an effort to raise awareness and funds in the fight against AIDS. The evening will be hosted by Eva Longoria and supported by the iconic fashion editor, Carine Roitfeld.

MAY 17TH-24TH: MAKING RED CARPET FIRSTS

From the Opening to the Closing Ceremonies and every day in between, L’Oréal Paris reaffirms its commitment to diversity and to cinema by continuing to promote exceptional talent and women from all corners of the globe. On the red carpet for this historic edition of Cannes both Elle Fanning, the newly announced global face of L’Oréal Paris, Deepika Padukone, the Bollywood star, Guan Xiaotong, the 19-year-old Chinese acting sensation and Wotan Wilke Möhring, the German-born actor make their festival debut for L’Oréal Paris. Representing the brand to the international audience at Cannes and watching at home. The Angolan-born model, Maria Borges, will also represent the brand for the first time at this 70th edition.

Follow Cannes with us at:
TWITTER @lorealMakeup @lorealhair
SNAPCHAT @lorealMakeup @lorealhair
TWITTER @lorealparis
FACEBOOK LorealParisOfficial
YOUTUBE LorealParisOfficial
#lorealparis #lorealcannes #OfficialPartner #20years #Cannes2017

Source: L’Oréal Paris

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May 19, 2017 at 10:59 am

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ASEAN Ministers Convene at Sunway University to Drive Regional SDG Agenda

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KUALA LUMPUR, Malaysia/PRNewswire/ — In late April 2017, thought-leaders including Ministers, Former Ministers and representatives from government bodies and prominent economists specializing in sustainable development from the ASEAN region and Australia gathered at Sunway University in Sunway City, Malaysia. The gathering at a two-day ASEAN Ministers Workshop 2017 (AMW) was to share and improve their respective national strategies, and to formulate a regional mechanism to implement the United Nation’s Sustainable Development Goals (SDGs) in Southeast Asia.

Datuk Seri Abdul Rahman Dahlan, Minister in the Prime Minister’s Department, Malaysia (3rd from left) and Tan Sri Dr Jeffrey Cheah AO, Chancellor of Sunway University (2nd from right) with distinguished members from the first Plenary Discussion at the ASEAN Ministers Workshop
Datuk Seri Abdul Rahman Dahlan, Minister in the Prime Minister’s Department, Malaysia (3rd from left) and Tan Sri Dr Jeffrey Cheah AO, Chancellor of Sunway University (2nd from right) with distinguished members from the first Plenary Discussion at the ASEAN Ministers Workshop
Among the ASEAN Ministers who attended the first of its kind workshop were: Datuk Seri Abdul Rahman bin Dahlan, Minister in charge of the Economic Planning Unit, Malaysia; Dr Bambang Brodjonegoro, Minister of National Development Planning, Indonesia; and Saleumxay Kommasith, Minister of Foreign Affairs, Lao PDR.

Tan Sri Dr Ramon V Navaratnam, Pro Chancellor of Sunway University welcomed all the delegates to the workshop. In his welcome speech he emphasized on the important role corporates and SMEs play in supporting sustainable development, citing that it is in their best interest to support sustainable development as it will benefit their businesses in the future.

“This first AMW will be the catalyst of an annual high-level event for the ASEAN Ministers to meet, discuss and work towards achieving the SDGs for the region. The Jeffrey Sachs Center on Sustainable Development (JSC) is committed to support the UN’s blueprint for ending poverty in the world in the context of sustainable development and building a sustainable future for all,” said Professor Woo Wing Thye, Chair, AMW Organizing Committee.

With three plenary discussions focused on the ASEAN Experience, the Australian Experience and the Action Items for Southeast Asia, the workshop also included a public lecture by Professor Jeffrey Sachs, Chairman of JSC and a dialogue with the attending ASEAN ministers.

Taking a question from a member of the audience, Professor Jeffrey Sachs shared that universities have an important role to play in helping ASEAN countries attain the SDGs through higher education. From the development of deep excellence in science, technology, engineering and areas essential to supporting sustainable policy development, Professor Jeffrey Sachs urged universities to consider becoming incubators for SDG start-ups.

During the plenary discussion on Implementing SDGs: The ASEAN Experience, keynote speaker Datuk Seri Abdul bin Rahman Dahlan spoke of Malaysia’s commitment to adopting the 2030 Agenda on Sustainable Development via the Eleventh Malaysia Plan (2016 to 2020). Looking forward to getting everyone to work together to make the world a better place, Abdul Rahman shared the willingness of Malaysia to work with regional and international partners towards making the 17 SDG goals a reality.

Among those who participated in the workshop were Dato’ Dr Abdul Rashid Abdul Malik, CEO, Pulau Banding Foundation; Professor John Thwaites, Co-chair SDSN Leadership Council and Chair Monash Sustainable Development Institute, Australia; Professor Gamini Herath, Professor of Economics, School of Business, Monash University Malaysia; Professor Phouphet Kyophilavong, Vice-Dean of Economics, National University of Lao; Professor Sumiani Yusoff, Dean, Sustainability Science Research Cluster, Universiti Malaya; Professor Noraini Tamin, IPBES, Expert of Land Degradation and Restoration; Rosemarie G Edillon, Undersecretary of the National Development Office for Policy and Planning, National Economic and Development Authority, Philippines; Dr Somkiat Triratpan, Secretary to the Minister attached to the Prime Minister’s Office, Thailand; Philip Green, First Assistant Secretary, Southeast Asia Mainland and Regional Division, Department of Foreign Affairs and Trade, Australia; Professor Vu Quoc Huy, Director, Institute of Regional Sustainable Development, Vietnamese Academy of Social Sciences; and Professor Graeme Wilkinson, Vice-Chancellor of Sunway University.

The workshop was sponsored and organized by the Jeffrey Cheah Foundation (JCF); and co-organized by the Jeffrey Sachs Center on Sustainable Development (JSC), Jeffrey Cheah Institute on Southeast Asia (JCI), Pulau Banding Foundation, UKM’s Lestari and hosted by Sunway University.

About the Jeffrey Sachs Center on Sustainable Development

The Jeffrey Sachs Center on Sustainable Development (JSC) was established through a substantial gift from the Jeffrey Cheah Foundation to the United Nations Sustainable Development Solutions Network to support the global effort to achieve the 17 Sustainable Development Goals set by the United Nations in 2015. The Center is housed at Sunway University in Kuala Lumpur, Malaysia. Its vision is to embed sustainable development practices in everyday life. JSC will collaborate with government agencies, private sector groups, and civil society to formulate public policies and actions to realize the UN’s Sustainable Development Goals. It will serve as the Southeast Asia regional hub of the Sustainable Development Solutions Network to promote green development and social progress through research and education.

For further queries, kindly contact the Jeffrey Sachs Center on Sustainable Development at jsc@sunway.edu.my.

Photo – https://photos.prnasia.com/prnh/20170502/1840138-1

Source: Sunway University

Written by asiafreshnews

May 8, 2017 at 3:31 pm

Posted in Uncategorized

Frost & Sullivan Lauds Aprima’s Ambulatory Revenue Cycle Management Platform for Expanding Customers’ Margins through Superior Collection Efficiency

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-Aprima effectively caters to ambulatory practices that require error-free claims processing and timely alerts on key RCM issues
SANTA CLARA, Calif. /PRNewswire/ — Based on its recent analysis of the ambulatory revenue cycle management (RCM) market, Frost & Sullivan recognizes Aprima® Medical Software, Inc. with the 2017 United States Frost & Sullivan Award for Product Leadership. In response to the urgent need for a range of advanced IT solutions that can also generate more net patient revenue, Aprima rolled out a series of RCM solutions, such as patient access, clinical documentation, claims processing, denials management, and outcomes measurement, which cover the entire value chain. Aprima is the RCM vendor of choice for numerous independent and hospital-owned physician practices, serving 70 specialties and sub-specialties in the United States. It boasts an industry-leading client retention rate of 98% due to its dedication to providing best-in-class technologies and reliable customer support.

Frost & Sullivan recognizes Aprima® Medical Software, Inc. with the 2017 United States Product Leadership Award.
Frost & Sullivan recognizes Aprima® Medical Software, Inc. with the 2017 United States Product Leadership Award.
“Aprima’s flagship RCM platform combines sophisticated technology and proven billing expertise to help US ambulatory practices completely outsource their RCM departments,” said Frost & Sullivan Industry Analyst Koustav Chatterjee. “These practices rely on Aprima to optimize cost and collection through better eligibility checking, claims editing, and denial management.”

Aprima’s technology, coupled with advisory services, allows these practices to reduce average account receivable (A/R) durations, enhance corporate revenues, and optimize regulatory compliance with regard to:

ICD 10 transition
Integration of Centers for Medicare & Medicaid Services’ (CMS’) rules
Prepayment audits
Adherence to physician quality reporting system (PQRS) reporting objectives
Aprima consolidates the pricing for most RCM components and enhances customers’ margins on collection because they are not required to invest in multiple external RCM vendors. This lowers the operational expenditure on RCM design and deployment.

Many medical practices lack the time and expertise to manage appeals and other billing issues that can result in thousands of dollars lost every month. Aprima RCM provides that focus and expertise, partnering with each practice to help increase reimbursements, speed up payment time, and reduce denials and underpayments. Furthermore, the company’s account management team helps practices identify coding omissions, and compares payments to payer contracted allowables, in order to help prevent underpayments. The team also assesses denials and offers regulatory support. On average, Aprima RCM customers are paid significantly faster than other RCM services and industry benchmarks.

Aprima’s claims engine has more than 20 million edits and a 98% clean claims rate. Its customers prefer doing business with Aprima due to its deep customer centricity and demonstrable results. On average, physician practices that leverage the Aprima RCM platform improve collection efficiency by 7% to 9% and increase revenue up to 29%.

“Aprima has emerged as the ideal RCM solution for ambulatory providers that are replacing their incumbent electronic health record vendors and or RCM vendors due to their inability to optimally enable value-based care principles,” noted Koustav. “Overall, its top-class RCM platform, customer acquisition strategy for new accounts, and evidence-based product enhancements for existing accounts will ensure its continued success through 2020.”

Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality, gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables.

Frost & Sullivan Best Practices awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research to identify best practices in the industry.

About Aprima® Medical Software, Inc.

Aprima provides innovative electronic health record (EHR), practice management (PM), population health and revenue cycle management (RCM) solutions for medical practices. For nearly two decades, the company has delivered quality solutions that have helped tens of thousands of users enhance patient care and satisfaction, as well as improve their practices’ bottom lines. Its EHR/PM solution sets the benchmark for ease-of-use, speed and flexibility, thanks to its single application, single database and customizable design that adapts automatically to individual physician workflows. Aprima has a proven track record of compliance with government initiatives, such as Meaningful Use and ICD-10, and has been awarded pre-validation status for NCQA PCMH recognition. The company is based in Richardson, Texas and performs all development, support, implementation and RCM services from within the U.S. To learn more about how Aprima can help your practice, please visit http://www.aprima.com, call us at 844 4APRIMA or email us at info@aprima.com.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today’s market participants. For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Contact us: Start the discussion.

Contact:

Clarissa Castaneda
P: 210.477.8481
F: 210.348.1003
E: clarissa.castaneda@frost.com

Joy Dinaro
Amendola Communications for Aprima
P: 847.809.0406
E: JDiNaro@ACMarketingPR.com

Photo – http://photos.prnasia.com/prnh/20170502/1839443-1

Source: Frost & Sullivan
Related Links:
http://www.frost.com

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May 8, 2017 at 3:05 pm

Posted in Uncategorized

Frost & Sullivan Lauds FourKites’ Customer-Focused Growth Strategy in the Supply Chain Tracking Market

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FourKites has built a cross-connected, scalable platform that aggregates siloed data and delivers unprecedented real-time freight visibility and orchestration

SANTA CLARA, California, May 2, 2017 /PRNewswire/ — Based on its recent analysis of the dynamic supply chain tracking solutions market, Frost & Sullivan recognizes FourKites with the 2017 North American Frost & Sullivan Award for Entrepreneurial Company of the Year. FourKites has built a unique solution that addresses the blue ocean of opportunities in shipper supply chain management (SCM). In the three years since its inception, FourKites has garnered a clientele of more than 30 of the leading shippers and third-party logistics providers (3PLs) in North America. It also received $16 million in funding from various venture capitalists, underlining the immense confidence of investors in its business model.

FourKites recognized that conventional freight tracking processes have massive blind spots that cost shippers heavily. In response, it started building software that would modernize information sharing in the $800 billion logistics industry and support high-quality, real-time data exchange among shippers, carriers, and 3PLs. Blue-chip shippers have been deploying FourKites’ solution to gain real-time visibility into and orchestration of their freight. In addition, eight of the top 30 3PLs rely on FourKites, thus unifying a host of systems to better control supply chain visibility.

“Instead of merely being a visibility platform, FourKites’ solutions offer real-time, actionable tracking data, and, more importantly, the orchestration tools to manage exceptions,” said Frost & Sullivan Industry Analyst, Silpa Paul. “The company has invested heavily in its capability to connect previously disparate systems for providing real-time visibility. The company has more than 15 bi-directional, working integrations with leading transportation management software providers, and connections to leading carrier and broker dispatch systems.”

Significantly, the company employs a people-powered, relationship-driven partnership model. The company collaborates with the customer to develop capabilities and solutions that deliver true value. It is not just a vendor application simply bolted onto a broader stack of technology, but an integral part of customers’ business.

FourKites’ value is further evident in its provision of a complimentary Visibility Assessment that applies anonymized customer data to a series of ROI categories, such as:

detention cost savings,
inventory reduction at distribution centers, and
efficiency gain/loss of inbound track and trace.
“FourKites is now a disruptive brand that enhances downstream production management and pushes both customers and partners to creatively apply modern technology,” noted Paul. “Meanwhile, its people-centric business model can remove supply chain and logistics inefficiencies to deliver a rich client experience.”

Each year, Frost & Sullivan presents this award to the company that has demonstrated excellence in devising a strong growth strategy and robustly implementing it. The recipient has shown strength in terms of innovation in products and technologies and leadership in customer value, as well as speed in response to market needs. In short, the award looks at the emerging market players in the industry and recognizes their best practices that are positioned for future growth excellence.

Frost & Sullivan Best Practices awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research to identify best practices in the industry.

About FourKites

FourKites is re-shaping the logistics industry for real-time transparency and efficiency. FourKites provides comprehensive real-time tracking and supply chain visibility solutions across transportation modes and digital platforms. Using FourKites, blue-chip shippers and 3PLs can share the same, real-time shipping location and status information – from more than 50 onboard GPS/ELD systems used by fleets to individual owner-operator smartphones and flip phones. FourKites helps enterprise customers save time and money across the transportation spectrum. Best of all, nothing falls through the cracks. Learn how FourKites real-time visibility and orchestration solution can help your business by requesting a demo at http://www.fourkites.com

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today’s market participants. For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Contact us: Start the discussion.

Contact:

Chiara Carella
P: +44 (0) 207.343.8314
F: 210.348.1003
E: chiara.carella@frost.com

Source: Frost & Sullivan
Related Links:
http://www.frost.com

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May 8, 2017 at 2:57 pm

Posted in Uncategorized

The Board of Investment of Thailand: EEC Jumpstart Brings Thailand Closer to Become Key ASEAN Investment and Technology Hub

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BANGKOK /PRNewswire/ — The Thai government emphasized on its readiness to jumpstart the new regional’s economic hub, the Eastern Economic Corridor (EEC), as infrastructure development under the EEC Scheme, including the capacity expansion of U-Tapao International Airport, is progressing as planned. The EEC Scheme is in the process of seeking approval from the National Legislative Assembly and will be soon implemented in later 2017.

Mr. Nattaporn Jatusripitak, Advisor to the Office of the PM (Far-left), together with four representatives from private sector: Mr. Hiroki Mitsumata, President of JETRO Bangkok (Left), Mr. Vikrom Kromadit, CEO of Amata Corporation PCL. (Right) and Mr. Narongsak Jivakanun, Executive Vice President, Corporate Strategy of PTTGC PCL. (Far-right) revealed after the meeting with PM on the EEC development plan and the capability of U-Tapao International Airport as the region’s aviation hub.
Mr. Nattaporn Jatusripitak, Advisor to the Office of the PM (Far-left), together with four representatives from private sector: Mr. Hiroki Mitsumata, President of JETRO Bangkok (Left), Mr. Vikrom Kromadit, CEO of Amata Corporation PCL. (Right) and Mr. Narongsak Jivakanun, Executive Vice President, Corporate Strategy of PTTGC PCL. (Far-right) revealed after the meeting with PM on the EEC development plan and the capability of U-Tapao International Airport as the region’s aviation hub.
The first meeting of the EEC Development Policy Committee, chaired by the Prime Minister Gen. Prayuth Chan-o-cha, agreed on the establishment of the “eastern aviation city,” or “Aeropolis,” in the vicinity of U-Tapao International Airport to help promote the EEC. There will be the development of three business groups in the future including Sattahip Commercial Port, a Specialized Medical Center, and defense technology. The meeting also agreed to have the State Railway of Thailand conduct the feasibility study on the development of high-speed train system linking Suvarnabhumi, Don Mueang & U-Tapao airports, to maximize the benefits of the “Aeropolis” to the country. The Policy Committee also endorsed the development plan for the Eastern Economic Corridor of Innovation (EECI) under the Ministry of Science and Technology in Wang Chan Valley and Rayong province and the Eastern Digital Innovation Park under the Ministry of Digital Economy and Society in Sri Racha, Chonburi.

In this occasion, Prime Minister Gen. Prayuth led a group of Thai and international media representatives to visit the new face of U-Tapao International Airport, which showcased the country’s capability to become the aviation hub of the region. Developed under the “One Airport, Two Missions” concept, U-Tapao International Airport was initially built for national security purpose but later expanded its capability to serve commercial aviation services. The group later visited the Maintenance, Repair and Overhaul Center located at the airport.

Aviation is among nine target industries being promoted in the three provinces in EEC area, in which key focuses are those involving high technology and extensive research and development, and crucial to the development of the country’s infrastructure and logistics, and promotion of tourism destinations in the areas. Other target industries are Next-Generation Automotive, Smart Electronics, Eco-friendly Petrochemicals and Bio-Chemicals, Automation and Robotics, Medical Hub, Affluent, Medical & Wellness Tourism, Food for the Future and Digital industries.

Prime Minister Gen. Prayuth said that, “The Thai government is keen to offer a full support to international investors in these target industries who strive to achieve sustainable development goals, bring a better quality of life to the local community and provide continuing opportunities for local SMEs. We have qualified workforce in the market, as well as utilized best efforts in mitigating investment obstacles and offering attractive privileges and incentives. Most importantly, the EEC Scheme, which was developed for constant and sustainable development, has now been approved by the Council of State and in the process of seeking the Cabinet’s approval.”

On the same day, the Prime Minister also met with 21 top business leaders in relevant organizations and industries including Amata Corporation Public Company Limited, The Japan External Trade Organization (JETRO), PTT Global Chemical Company Limited, Senior Aerospace (Thailand) Limited, BMW etc.

Amata affirmed the EEC development supported both local and international investment to align with Thailand 4.0 roadmap, through the recent collaboration with Yokohama Smart City Project provides the blueprint of development of smart city in Amata Nakorn Industrial Estate reduce power consumption and the ambition to build the city of education with a total of 7 educational institutes in the estate.

JETRO expressed that Japanese investors were confident on the clear direction of the EEC project and optimistic about the Thai government’s recent announcement of Investment Promotion Act 2017.

According to Senior Aerospace, to be a part of the new EEC program is a good opportunity to educate local people as well as learn from them, while strengthening the mutual relationship, as well as marks the beginning of business expansion into the future where they foresaw more and more new players in the aviation sector.

PTTGC, as a veteran investor in the areas, expressed readiness to embrace new business partners in value-added industry sectors.

The Board of Investment of Thailand (BOI) set new chapter of investment promotion – Investment 4.0 to align with the Thai government’s Thailand 4.0 policy, which takes into account the shifting to value-based, innovation-driven economy, the development of human capital, and the creation of high value service. BOI’s mission to promote investment in the EEC focuses on core technologies that Thailand has strong potential, including biotech, nanotech, advanced material and digital technology. This is in line with BOI’s.

According to the BOI, those investing in EEC area will enjoy special incentives that are highly competitive and considered ‘most enticing ever’ offered in Thailand. These include 50% deduction on corporate income tax (CIT) for five years in addition to a CIT exemption of 13 years and other incentives granted in line with the Competitive Enhancement Act, which includes a maximum corporate income tax exemption of 15 years, among others. The government will also provide other supports including eliminating barriers, rules and regulations in order to generate real, high-value investments as well as One Stop Service to facilitate investment in the area.

The EEC, consisting of three Eastern provinces Chachoengsao, Chonburi and Rayong, is expected to be a flagship investment and technology hub of Thailand and reshape the future of the country. The development of EEC will bring a great deal of benefits to other regions of Thailand as it directly connects to other Eastern provinces including Prachin Buri, Srakaew, Chantaburi and Trad, as well as serve as economic link between upper and lower Northeastern region, and the Gulf of Thailand.

For more information, please contact
Name: Apichaya Sophonratana
Tel: +662-553-8111 Ext. 6932
E-mail: thailandinvestmentyear@gmail.com or visit http://www.boi.go.th

Photo – https://photos.prnasia.com/prnh/20170502/1840174-1

Source: The Board of Investment of Thailand (BOI)

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May 8, 2017 at 2:53 pm

Posted in Uncategorized

SWIFT and banks in the Philippines join forces to achieve greater automation for Filipino corporates

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The launch of the Philippines guidelines for Account Reporting (MT940) will help Filipino corporates optimise their finance operations

MANILA, Philippines, May 2, 2017 /PRNewswire/ — SWIFT announces today the publication of the Philippines (PH) MT940 guidelines, marking a successful completion of the first phase of the Corporate-to-Bank (C2B) initiative. Announced in January 2016, the initiative aims at aligning the communications standards between corporates and banks in the domestic Filipino market. The guidelines were developed with the support of 25 global and local banks along with 10 corporates including Ayala Land, Globe, and Meralco.

Leveraging international best practices and keeping in mind the Filipino market specific requirements, the initiative will bring greater levels of automation and standardisation to multi-banked corporates, enabling improved straight through processing (STP) using MT940 for auto-reconciliation of bank statements and consolidated cash visibility, all on one single platform. By providing a forum to define enhanced standardisation in the Philippines financial community, SWIFT is playing an essential role as it brings the community together to identify and overcome current challenges.

The first phase of the C2B initiative is now completed with the launch of the Account reporting (MT940) guidelines for the Philippines. The initiative is carrying on with its mission to develop a standard language for Corporate-to-Bank message flow in accordance with global and domestic market practices. The next phases will see the C2B initiative defining common standards for payment instructions (Phase 2), foreign exchange confirmations, fixed deposits and fixed loans confirmation (Phase 3). The C2B initiative will bring greater alignment between corporates and banks on financial requirements. SWIFT is committed to enable the PH C2B guidelines and foresees strong adoption by the financial community of these newly developed standards in the coming months.

Lisa O’Connor, Head of Standards, Asia Pacific at SWIFT said: “It is great to see so many banks and corporates participating to SWIFT’s Corporate-To-Bank initiative. The launch of the PH MT940 guidelines is a display of the industry’s capability in collaborative innovation. We live in a world of speed and interconnectivity. When it comes to guidelines, focus on standardisation should be a priority with international regulations and making sure auto reconciliation goes smoothly. Our C2B initiative will drive improved communication between corporates and banks following global standards. This is a great project for SWIFT and the domestic Filipino community through the drive to improve existing message flow and combine it with well-defined international standards to support the strongly developing Filipino economy. As the community becomes more aware of the value of these guidelines, we expect an increase in adoption.”

Isabelita M. Papa, Philippines NMG Chairperson and SWIFT User Group Chairperson said: “This initiative is a further proof of the power of collaboration as the Philippines community and SWIFT came together to align the communication standards between corporates and banks. In the larger context of ASEAN integration, this is a critical step to drive efficiency in the Filipino economy as it aligns closely with AEC 2025 goals and global trends such as ISO 20022 adoption. The Corporates-to-Banks initiative is a fantastic example of the private sector responding to these evolving needs”.

Notes to Editor:

In addition to the participation of the central bank of the Republic of the Philippines, Bangko Sentral ng Pilipinas, below is the full list of banks that took part and actively supported the development of the guidelines:

1.

Asia United Bank

2.

BDO Bank

3.

BAML

4.

Bank of the Philippine Islands

5.

Chinabank

6.

Citibank

7.

Deutsche Bank

8

Development Bank of the Philippines

9.

East-West Bank

10.

HSBC

11.

J.P. Morgan Chase Bank, N.A.

12.

Land Bank of the Philippines

13.

Maybank

14.

Metrobank

15.

Mizuho

16.

Philippine Bank of Communications

17.

Philippine National Bank

18.

Rizal Commercial Banking Corporation

19.

Robinsons Bank Corp.

20.

Security Bank

21.

SMBC

22.

Standard Chartered

23.

Union Bank of the Philippines

24.

United Coconut Planters Bank

25.

Bangko Sentral ng Pilipinas*

About SWIFT for Corporates

SWIFT for Corporates offers a wide and growing range of products and services for multi-banked corporates to connect with banks and financial institutions through a single, secure and reliable channel. SWIFT provides corporate treasurers and finance managers global visibility on cash and trade, lower cost of financial transactions and improved security and reliability. SWIFT for Corporates also includes additional capabilities such as Bank Payment Obligation (BPO)/Trade Services Utility (TSU), 3SKey, SWIFTRef, MyStandards and Sanctions Screening. For more information, visit http://corporates.swift.com/

About SWIFT

SWIFT is a global member-owned cooperative and the world’s leading provider of secure financial messaging services. We provide our community with a platform for messaging, standards for communicating and we offer products and services to facilitate access and integration; identification, analysis and financial crime compliance. Our messaging platform, products and services connect more than 11,000 banking and securities organisations, market infrastructures and corporate customers in more than 200 countries and territories, enabling them to communicate securely and exchange standardised financial messages in a reliable way. As their trusted provider, we facilitate global and local financial flows, support trade and commerce all around the world; we relentlessly pursue operational excellence and continually seek ways to lower costs, reduce risks and eliminate operational inefficiencies. Headquartered in Belgium, SWIFT’s international governance and oversight reinforces the neutral, global character of its cooperative structure. SWIFT’s global office network ensures an active presence in all the major financial centres.

For more information, visit http://www.swift.com or follow us on Twitter: @swiftcommunity and LinkedIn: SWIFT

Contact:
Kathy Kwan
Communications Specialist, Asia Pacific
SWIFT
+852-2107-8451
kathy.kwan@swift.com

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May 8, 2017 at 2:51 pm

Posted in Uncategorized

Hotmob Launches ALCANZAR: A Safety-First Demand Side Platform

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HONG KONG/PRNewswire/ — Hotmob today announced the launch of a safety-first demand side platform (DSP) which focus on quality, brand safety and transparency.

In the wake of recent reports on display and videos ads running next to unsafe content on YouTube, major brands and media buying agencies reacted by suspending their advertising budget from Google’s programmatic solutions. As a result of brand safety concerns, Hotmob launches a safety-first demand side platform to address such issue by customizing its brand protection strategy for advertisers.

Hotmob CEO Johnny Wong said, “We understand how important brand safety is for brands and advertisers as we have over 10 years of experience in managing and serving premium digital advertising. We have a whitelist established with hand-picked apps and websites to ensure ads are delivered in safe environment through our DSP.”

Hotmob developed a proprietary safety-first demand side platform (DSP) named ALCANZAR with a focus on providing quality inventory, safeguarding brands by applying category filters and content parameters to measure whether a publisher’s content meets the brand’s specific needs. Both pre-bid and post-bid screening is applied to increase brand-safety controls by allowing advertisers to screen the URL or site section, therefore offering more transparency on where ads are running.

One of the unique features of ALCANZAR is that ad inventories are purchased in real time with smart bidding algorithms and price optimization. That is, only the necessary impressions are purchased at the best possible price point. The DSP platform adopts contextual ranking powered by artificial intelligence technology to analyse millions of ad inventory in apps and websites and determines the most relevant placement to a brand’s product or service.

Advertisers can access more than 10 billions of ad slots each day from multiple inventory sources across major global ad exchanges including Google, YouTube, Smaato, Pinyou and more. Online display, video and mobile ad inventories can be bought on CPM basis and the ad formats are compliant to IAB and international standards, hence maximizing the reach to targeted audience.

About Hotmob

Hotmob is the leading mobile marketing company that operates a hybrid mobile advertising marketplace to offer premium and performance-driven mobile advertising solutions, which are facilitated by proprietary advertising technologies and robust ad-serving platforms to meet the growing demand from businesses across Asia.

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May 5, 2017 at 11:37 am

Posted in Uncategorized

Veritas Study: Organizations Worldwide Fear Non-compliance with New European Union Data Regulation Could Put Them Out of Business

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-Nearly half of organizations are afraid they won’t meet the requirements of the General Data Protection Regulation, inadequate technology cited as core challenge

SINGAPORE /PRNewswire/ A global study from Veritas Technologies, the leader in information management, has revealed that 86 percent of organizations worldwide are concerned that a failure to adhere to the upcoming General Data Protection Regulation (GDPR) could have a major negative impact on their business. Nearly 20 percent said they fear that non-compliance could put them out of business. This is in the face of potential fines for non-compliance as high as $21 million or four percent of annual turnover – whichever is greater.

Intended to harmonize the governance of information that relates to individuals (“personal data”) across European Union (EU) member states, the GDPR requires greater oversight of where and how personal data—including credit card, banking and health information—is stored and transferred, and how access to it is policed and audited by organizations. GDPR, which takes effect on May 25, 2018, will not only affect companies within the EU, but extend globally, impacting any company that offers goods or services to EU residents, or monitors their behavior, for example, by tracking their buying habits. The study indicates that a whopping 47 percent of organizations globally have major doubts that they will meet this impending compliance deadline.

The research findings from The Veritas 2017 GDPR Report, which surveyed more than 900 senior business decision makers in 2017 across Europe, the U.S. and Asia Pacific, also found that more than 20 percent (21%) are very worried about potential layoffs, fearing that staff reductions may be an inevitable outcome as a result of financial penalties incurred as a result of GDPR compliance failures.

Figure 1: “What concerns you the most about the potential fallout from your organization not being in compliance with the GDPR?
Figure 1: “What concerns you the most about the potential fallout from your organization not being in compliance with the GDPR?

Companies are also worried about the impact non-compliance could have on their brand image, especially if and when a compliance failure is made public, potentially as a result of the new obligations to notify data breaches to those affected. 19 percent of those surveyed fear that negative media or social coverage could cause their organization to lose customers. An additional one in ten (12%) are very concerned that their brand would be de-valued as a result of negative coverage.

Lack of Technology Hindering GDPR Compliance

The research also shows that many companies appear to be facing serious challenges in understanding what data they have, where that data is located, and its relevance to the business – a critical first step in the GDPR compliance journey. Key findings reveal that many companies are struggling to solve these challenges because they lack the proper technology to address compliance regulations.

Almost one third (32%) of respondents are fearful their current technology stack is unable to manage their data effectively, something that could hinder their ability to search, discover and review data – all essential criteria for GDPR compliance.

In addition, 39 percent of respondents say their organization cannot accurately identify and locate relevant data. This is another critical competency as the regulation mandates that, when requested, businesses must be able to provide individuals with a copy of their data, or delete it, within a 30 day time frame.

There is also widespread concern about data retention. More than 40 percent (42%) of organizations admitted that there is no mechanism in place to determine which data should be saved or deleted based on its value. Under GDPR, companies can retain personal data if it is still being used for the purpose that was notified to the individual concerned when the data was collected, but must delete personal data when it is no longer needed for that purpose.

Investing in GDPR Compliance

Veritas’ research found that less than one third (31%) of respondents believe their organization is GDPR ready. For those working towards compliance, seven figure investments are the norm. On average, firms are forecasting spending in excess of $1.4m on GDPR readiness initiatives.

Potential Compliance Challenges Globally

Many businesses around the world have a long way to go towards GDPR compliance.

  • Lack of GDPR Readiness: The research highlights that several countries are way behind their global counterparts in terms of GDPR readiness. Singapore, Japan and the Republic of Korea came in last place in the survey on this topic. Fifty-six percent of respondents in Singapore fear they will be unable to meet the regulatory deadlines. The situation is worse in Japan and the Republic of Korea, where that percentage is greater than 60 percent.
  • Fear of Going Out of Business: When it comes to fears of going out of business as a result of compliance issues, the concerns are greatest in the U.S. and Australia. Nearly 25 percent of respondents in both countries fear that non-compliance could threaten the very existence of their organizations.
  • Concerns About Layoffs:  Likewise, respondents in the United States and Australia are also the most concerned that penalties from GDPR non-compliance could lead to layoffs. Twenty-six per cent of respondents in the U.S. expressed concern about potential workforce reductions, and that number climbs to nearly 30 percent in Australia. This was also the number one concern in the Republic of Korea, where 23 percent of respondents stated they fear layoffs are a distinct possibility.
  • Worry of Brand Damage: In Asia Pacific, businesses appear to be very worried about the impact a compliance failure could have on their brand reputation. Twenty percent of respondents in Singapore fear they could lose customers because of negative media and social coverage. The number increases in 21% in Japan and the Republic of Korea.

“There is just over a year to go before GDPR comes into force, yet the ‘out of sight, out of mind’ mentality still exists in organizations around the world. It doesn’t matter if you’re based in the EU or not, if your organization does business in the region, the regulation applies to you,” said Mike Palmer, executive vice president and chief product officer at Veritas. “A sensible next step would be to seek an advisory service that can check the level of readiness and build a strategy that ensures compliance. A failure to react now puts jobs, brand reputation and the livelihood of businesses in jeopardy.”

For information on how organizations can become GDPR compliant visit our website or click here to register for our upcoming GDPR Webinar with IDC and William Fry on April 25, 2017 at 8am PDT.

Research Methodology

Veritas commissioned independent technology market research specialist Vanson Bourne to undertake the research.

A total of 900 business decision makers were interviewed in February and March 2017 across the US, the UK, France, Germany, Australia, Singapore, Japan and the Republic of Korea. The respondents were from organizations with at least 1,000 employees, and could be from any sector. To qualify for the research, respondents had to be from organizations which do at least some business within the EU and therefore hold personal data on EU residents.

About Veritas Technologies

Veritas Technologies enables organizations to harness the power of their information, with information management solutions serving the world’s largest and most complex environments. Veritas works with organizations of all sizes, including 86 percent of global Fortune 500 companies, improving data availability and revealing insights to drive competitive advantage. www.veritas.com

Forward-looking Statements: Any forward-looking indication of plans for products is preliminary and all future release dates are tentative and are subject to change at the sole discretion of Veritas.  Any future release of the product or planned modifications to product capability, functionality, or feature are subject to ongoing evaluation by Veritas, may or may not be implemented, should not be considered firm commitments by Veritas, should not be relied upon in making purchasing decisions, and may not be incorporated into any contract.

Veritas, the Veritas Logo, NetBackup, Backup Exec and Enterprise Vault are trademarks or registered trademarks of Veritas Technologies LLC or its affiliates in the U.S. and other countries. Other names may be trademarks of their respective owners.

PR Contacts

APJ Contact
Veritas Technologies
Belinda Lim
+65 64275564
belinda.lim@veritas.com

Media Contact
Text100 Singapore
Mizu Chitra/Marc Lee
+65 66039000
veritas@text100.com.sg

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Source: Symantec Asia Pacific Pte Ltd

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April 27, 2017 at 12:31 pm

Posted in Uncategorized

SIR-Spheres(R) Y-90 Resin Microspheres Substantially Improves Quality of Survival in Primary Liver Cancer, New Study Against Standard Treatment Shows

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AMSTERDAM /PRNewswire/ —

459-patient SARAH Study shows that local treatments of advanced or inoperable Hepatocellular Cancer (HCC) with SIR-Spheres Y-90 resin microspheres did not lead to a planned superiority difference in overall survival compared to daily standard-of-care systemic therapy with sorafenib, yet had significantly reduced side effects and better Quality of Life

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.[1]

generated by system

The results, which could impact the treatment of tens of thousands of liver cancer patients annually, were announced by the principal investigator of the SARAH study, Professor Valerie Vilgrain MD, PhD, Department of Radiology, Beaujon Hospital, Assistance Publique – Hopitaux de Paris (AP-HP) and Universite Paris Diderot, Sorbonne Paris Cité, France.

“Neither sorafenib nor SIR-Spheres Y-90 resin microspheres produced a statistically significant difference in Overall Survival (OS) of the patients we studied,” said Prof. Vilgrain.  “Despite 26.6% of patients in the SIRT arm not receiving SIR-Spheres per protocol, the primary endpoint of Overall Survival by intention-to-treat [ITT] was not significantly different (median 8.0 vs. 9.9 months; p=0.18). Moreover, if we look at the patients who received SIR-Spheres or sorafenib according to the SARAH protocol, median OS was identical (9.9 vs. 9.9 months; p=0.92).”

“In terms of what matters for patients, the findings from this first large head-to-head comparison of liver-directed Selective Internal Radiation Therapy (SIRT) and systemic chemotherapy with sorafenib also show clearly that liver-directed procedures with SIR-Spheres result in a significantly better tolerance of treatment and quality of life,” Prof. Vilgrain stated.  “I believe this consideration should be a critical factor in selecting first-line treatment for this patient population in the future.”

The difference in the frequency and severity of side effects of patients treated with SIR-Spheres Y-90 resin microspheres versus sorafenib was striking. Significantly fewer patients treated with SIR-Spheres Y-90 resin microspheres had any treatment-related side effects at all (76.5% vs. 94.0% for sorafenib; p<0.001), and these were also less severe (≥ grade 3; 40.7% vs. 63.0%, respectively; p<0.001). Moreover, those patients treated with SIR-Spheres Y-90 resin microspheres who reported treatment-related side effects experienced a median of only 5 such events over the course of the SARAH study, compared to a median of 10 events in those who received sorafenib (p<0.001).

General treatment-related symptoms such as fatigue (42% vs. 65%; p<0.001), abdominal pain (20% vs. 29%; p=0.032), nausea or vomiting (12% vs. 23%; p=0.001) and infection (4% vs. 11%; p=0.007) were also significantly less frequently reported and less severe for patients receiving SIR-Spheres Y-90 resin microspheres, compared to sorafenib.

Fewer patients receiving SIR-Spheres Y-90 resin microspheres experienced treatment-related diarrhoea (13% vs. 68% for sorafenib; p<0.001), hand-foot skin reaction (0.4% vs. 21%; p<0.001), anorexia (13% vs. 32%; p<0.001), weight loss (6% vs. 21%; p<0.001) and alopecia (0% vs. 16%; p<0.001), as well as infections (4% vs. 11%; p=0.007), hypertension (3% vs. 13%; p<0.001) and non-gastrointestinal haemorrhage (3% vs. 10%; p=0.002).

There were few potential SIRT-associated treatment-related complications and, importantly, no radioembolization-induced liver disease (radiation hepatitis) experienced. There were no significant increases for SIR-Spheres Y-90 resin microspheres in gastrointestinal (GI) ulceration (2% vs. 0.5% for sorafenib; p=0.37) including one case of radiation-induced GI ulcer, ascites (12% vs. 11%; p=0.57), hyperbilirubinemia (12% vs. 13%; p=0.86) and only one case of radiation pneumonitis (0.4% vs. 0; p=0.46).

The results of Quality of Life (QoL) surveys filled out by SARAH participants at three month intervals after their initial treatment underscored the benefit of SIR-Spheres Y-90 resin microspheres. “Based on their responses to the Global Health Status questions in the European Organisation for Research and Treatment of Cancer [EORTC] QLQ-C30 questionnaire, patients treated with SIR-Spheres maintained their health status over the duration of the SARAH study, whereas patients receiving sorafenib reported a significant and sustained decline in QoL (group effect: p=0.005; time effect: p<0.001; between group difference increase over time: p=0.045),” Prof. Vilgrain said.

“In addition,” she noted, “we found that the tumours of patients treated with SIR-Spheres had a higher objective response (19.0% vs. 11.6%; p=0.042) than was seen with sorafenib, and experienced a significantly reduced risk of their cancer progressing in the liver, which is the main cause of death from this disease.”

Background of the SARAH Study

“Patients with HCC who are not eligible for liver transplant, surgery or ablation to treat their tumours in place face a very bleak prognosis of one or two years of life with increasing debilitation and pain,” Prof. Vilgrain said.  “In many cases, the patient’s HCC is already so advanced that the main treatment option available is sorafenib. In other cases, we are able to treat patients with intermediate-stage disease initially with several courses of chemotherapy infused directly into their livers, which is called transarterial chemoembolisation, or TACE, but this approach may fail.”

“For patients with advanced HCC or those failing TACE, we have for the past ten years relied upon oral systemic treatment with sorafenib, which was shown to extend survival compared to placebo, but also causes many side effects that can compromise patients’ quality of life.  That is why we decided to see if treatment with a newer form of liver-directed therapy, selective internal radiotherapy, or SIRT, with SIR-Spheres could represent a better alternative.  Our decision to initiate the SARAH study was based on smaller previous studies and retrospective analyses, which suggested that SIR-Spheres could be at least as effective and was well tolerated by HCC patients,” she stated.

The randomized, controlled, open-labelled SARAH (SorAfenib versus Radioembolization in Advanced Hepatocellular carcinoma) study directly compared the efficacy of selective internal radiation therapy (SIRT, or radioembolisation) using yttrium-90 [Y-90] resin microspheres (SIR-Spheres Y-90 resin microspheres, Sirtex Medical Limited, Sydney, Australia) versus sorafenib (Nexavar®, Bayer HealthCare Pharmaceuticals, Berlin, Germany).

SARAH was launched in December 2011 and concluded enrolment in February 2015.

With 459 patients treated in 25 clinical centres across France, SARAH is the largest randomized study ever to compare selective internal radiation therapy – or any liver-directed therapy – against the standard-of-care systemic therapy in the treatment of primary liver cancer.  Almost 70% of the patients in the SARAH study had advanced HCC (Barcelona Clinic Liver Cancer stage C), with portal vein thrombosis and no extrahepatic spread. Most of the other patients had failed two cycles of TACE.

Results of SIRveNIB, a parallel study in more than 360 Asia Pacific HCC patients will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on 4 June 2017.

What is Hepatocellular Carcinoma (HCC)?

HCC patients represent 90% of all people diagnosed with primary liver cancer, which is the sixth most common cancer in the world and the second leading cause of cancer-related death.  HCC affects mainly patients with cirrhosis from any cause, including viral hepatitis, alcohol misuse, and fatty liver disease, and results in more than 670,000 deaths globally each year.[2] Among people at risk of HCC, incidence of the disease increases progressively with advancing age, reaching a peak at around 70 years.[3]

Overall, one-third of patients with liver cirrhosis will develop HCC during their lifetime.[4]

  • Worldwide, approximately 54% of HCC cases can be attributed to HBV infection (affecting 400 million people) while 31% can be attributed to HCV infection (affecting 170 million people).[3]
  • In Africa and East Asia, the largest attributable fraction is due to HBV infection (60%), while in the developed Western world, chronic HCV infection appears to be the major risk factor.[5],[6]

In addition to these causes, it is now thought that up to one in eight (12.8%) of non-alcoholic steatohepatitis (NASH) patients with cirrhosis will progress to HCC.[7] NASH – which is widely considered to be triggered by type II diabetes, insulin resistance, obesity, hyperlipidaemia and hypertension – has become the number one cause of liver disease in Western countries.  Progression of NASH dramatically increases the risks of cirrhosis, liver failure, and HCC.  This is thought to be related to the worldwide epidemic of diabetes and obesity.[8]

HCC occurs more often in men than women, except in Africa, where more women are affected.[2]

What is SIRT with SIR-Spheres Y-90 resin microspheres?

SIRT with SIR-Spheres Y-90 resin microspheres is an approved treatment for inoperable liver tumours. It is a minimally-invasive treatment that delivers high doses of high-energy beta radiation directly to the tumours.  SIRT is administered to patients by interventional radiologists, who infuse millions of radioactive resin microspheres (diameter between 20-60 microns) via a catheter into the liver arteries that supply blood to the tumours. By using the tumours’ blood supply, the microspheres selectively target liver tumours with a dose of radiation that is up to 40 times higher than conventional radiotherapy, while sparing healthy tissue.

SIR-Spheres Y-90 resin microspheres are approved for use in Argentina, Australia, Brazil, the European Union (CE Mark), Switzerland, Turkey, and several countries in Asia for the treatment of unresectable liver tumours. In the US, SIR-Spheres Y-90 resin microspheres have a Pre-Market Approval (PMA) from the FDA and are indicated for the treatment of unresectable metastatic liver tumours from primary colorectal cancer with adjuvant intra-hepatic artery chemotherapy (IHAC) of FUDR (floxuridine).

References:

  1. Vilgrain V et al.  The International Liver Congress™ 2017 – 52nd annual meeting of the European Association for the Study of the Liver, J Hepatol 2017; 66 (Suppl 1): Abs. GS-012.
  2. Extrapolated from Ferlay J et al.  Globocan 2012. v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. Available from: http://globocan.iarc.fr, accessed on 14/April/2017.
  3. EASL-EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma.  J Hepatol 2012; 56: 908-43.
  4. Sangiovanni A et al.  Hepatology 2006; 43: 1303-10.
  5. Di Bisceglie AM.  Hepatology 2009; 49(Suppl 5): S56-60.
  6. Davis GL et al.  Proc (Bayl Univ Med Cent) 2008; 21: 266-80
  7. White DL et al.  Clin Gastroenterol Hepatol 2012; 10: 1342-59.
  8. World Gastroenterology Organisation Global Guidelines: Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis, 2012.

SIR-Spheres® is a Registered Trademark of Sirtex SIR-Spheres Pty Ltd.

562-EUA-0417

Source: Sirtex Medical Limited

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Written by asiafreshnews

April 25, 2017 at 4:19 pm

Posted in Uncategorized