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Archive for April 5th, 2016

Switzerland: Exclusive Journey of Discovery Into the Longest Train Tunnel in the World

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ZURICH /PRNewswire/ — The Gotthard Base Tunnel, the longest train tunnel in the world, enters into service on 11 December 2016. Prior to this, the record-breaking construction will be more accessible than ever, but only for a limited period: from 2 August 2016, passengers may descend into the once-in-a-century construction on exclusive tunnel rides – disembarkation in the depths of the mountain included. The special “Gottardino” train only runs until 27 November 2016 and the number of tickets is limited.

(Photo: http://photos.prnewswire.com/prnh/20160323/347230)
(Photo: http://photos.prnewswire.com/prnh/20160323/347231)

The test operation of the Gotthard Base Tunnel is in full swing. The handover of the longest train tunnel in the world by constructor Alp Transit Gotthard AG to its future operators, Swiss Federal Railways SBB, will take place in two months’ time, on 1 June 2016, after 17 years of construction.

Catching a train deeper into the mountain than ever before

Before regular operations of the Gotthard Base Tunnel commence on 11 December 2016, SBB is giving customers the opportunity to admire the interior of the once-in-a-century construction. From 2 August to 27 November 2016, the special “Gottardino” train will carry visitors to a record depth in the rock of the Swiss Alps. A special stop will be made at the multifunction station in Sedrun. Here, 800 metres below the surface, a tour will vividly demonstrate the dimensions of the gigantic tunnel system.

Once trains are travelling through the Gotthard Base Tunnel at high speed, a stop in the middle of the tunnel will no longer be possible. Thanks to the new north-south connection, regions and neighbouring countries on both sides of the Gotthard Tunnel will move closer together. From the end of 2016, passengers will cross the Alps in the new tunnel in only 20 minutes and reach their destination faster than ever.

Information about the sales outlets of Swiss Travel System are available at http://www.SwissTravelSystem.com/wheretobuy.

More information about the Gotthard Base Tunnel or story ideas about the once-in-a-century construction are available at http://www.SwissTravelSystem.com/gotthard or by request from media@swisstravelsystem.com.

– Cross reference: Picture is available at AP Images (http://www.apimages.com) –

Contact: Tabea Mandour, Tel: +41(0)44-225-80-40

Source: Swiss Travel System AG

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April 5, 2016 at 3:58 pm

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2015 Another Record Year for Convention Destination Vienna

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VIENNA /PRNewswire/ — Viennas meetings industry recorded more events and overnights than ever before in 2015. The resulting value-added broke the billion euro barrier for the first time ever.

(Photo: http://photos.prnewswire.com/prnh/20160331/350052)
(Photo: http://photos.prnewswire.com/prnh/20160331/350053)

“The conference destination Vienna achieved record results for all key indicators in 2015,” reports Norbert Kettner, Director of the Vienna Tourist Board. Vienna hosted a total of 3,685 congresses, corporate conventions and incentives in 2015. The resulting overnights totaled 1.7 million, an increase of 13% on the previous year.” The contribution made by Vienna’s meetings industry to Austria’s national value-added rose by 16% compared to 2014 to1.04 billion euros, a remarkable increase that broke the billion euro barrier for the first time,” according to Kettner. 81% of value-added was attributable to international congresses, which brought in half the total number of meeting delegates and 76% of overnights in 2015. Meetings, congresses and incentives in Vienna secured more than 19,000 year-round jobs throughout Austria. Overall the Austrian capital recorded 14.3 million overnights in 2015, 12% of which was due to the meetings industry.

For years now, the International Congress and Convention Association (ICCA) has ranked Vienna among the top three congress metropolises worldwide. “Vienna scores as an easily accessible central European hub, with optimal support from urban and scientific institutions, a multifaceted hotel sector, and top meeting locations,” explains Kettner. “Congress delegates spend an average 534 euros a day in Vienna, and almost half of them plan a private return visit.” Vienna – which can be reached by direct flights from over 180 destinations worldwide – currently offers around 65,000 hotel beds. Further information: http://www.vienna.convention.at.

– Cross reference: Picture is available at AP Images (http://www.apimages.com) –

Further information:

Vienna Tourist Board
Isabella Rauter
Tel: +43/1/211 14-301
E-mail: media.rel@vienna.info

Source: Vienna Tourist Board

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April 5, 2016 at 3:48 pm

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Rising Media to Hold the 3rd Annual ‘Inside 3D Printing Conference & Expo’, Asia’s Largest 3D Printing Tradeshow on June 22-24, 2016 in Seoul

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HONG KONG /PRNewswire/ — 3D Printing technology continues to evolve and expand. The 3rd annual Inside 3D Printing Conference & Expo will take place in Seoul on June 22-24, 2016 at KINTEX. This is a must-attend trade show and conference for everyone involved in or looking to learn more about this revolutionary industry.

This is the largest 3D Printing event in Korea and one of the most important and state-of-the-art 3D Printing tradeshows in Asian region. This year’s event promises to be even more exciting and vibrant than ever before with soaring popularity of brand-new AM (Additive Manufacturing) technologies applicable to various fields throughout the whole globe.

Participating at ‘Inside 3D Printing Conference & Expo 2016 – Seoul‘ will enable you to explore and discover the diverse uses and technologies of 3D Printing. You will learn valuable insights from experts around the world who will share how 3D Printing is shaping and revolutionizing manufacturing, rapid prototyping, fashion design, aviation, architecture, medical and more. There will be over 100 local and international companies exhibiting and an outstanding line up of expert speakers.

The exhibition will include a vast array of exhibitors and sponsors giving you the opportunity to learn and experience the latest products and services covering the entire 3D Printing ecosystem. These will include 3D printers, 3D scanners, CAD/CAM software, printing materials, platform service and much more.

Inside 3D Printing – Seoul is sponsored by 80+ worldly renowned sponsors including MakerBot (Platinum) and HanilProtech (Silver). Major Korean 3D printing manufacturers as Hyvision, Hepzibah, TPC Mechatronics, OTS, Carima, 3D Box, Vistech Korea, Samdi Technology, Pensees in addition to global brand companies like Hoganas (Sweden), Esun (China) and XYZ Printing (Taiwan).

The Inside 3D Printing Conference will consist of 4 categories – Metal, Manufacturing, Business and Medical – which enables each registrant to attend the sessions most relevant to them. Breakout sessions will provide deep-dive into specific topics of 3D printing technology and its application in areas like manufacturing, medicine, M&A, copyright & intellectual protection, metal components, etc.

The conference program includes world-famous keynote speakers including Terry Wohlers (Principal Consultant of Wohlers Associates, Inc.), Jonathan Jaglom (CEO, MakerBot).

This year’s event will have two news additions, the Inside 3D Printing Startup Pitch with the winning prize of the investment amount of KRW 5,000,000 from Asimov Ventures and 3D Print Design Show displaying the latest designs and achievements made in 3D Printing. Both of these will take place during the event.

To learn more and to register, please visit our website (www.inside3dprinting.com/seoul) or contact Inside 3D Printing Secretariat at inside3dprinting@kintex.com for more detailed information.

Media contact:

Christoph Rowen
Tel: +852 9190 4412
Email: crowen@risingmedia.com

Source: Rising Media

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April 5, 2016 at 3:40 pm

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Total and Kia Renew Partnership

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SEOUL, South Korea /PRNewswire/ —

Total Lubrifiants will remain Kias recommended and exclusive partner for automotive lubricants for a further 5 years.

Kia Motors Corporation and Total Lubrifiants recently renewed their strategic partnership agreement. For another 5 years, Total will remain Kia Motors Corporation’s preferred aftermarket lubricants supplier for Kia vehicles. Total branded automotive lubricants will be exclusively recommended and available to customers across Kia’s service network of more than 5,500 dealers in around 180 countries, including West European markets from January 1st, 2017.

(Logo: http://photos.prnewswire.com/prnh/20160401/350463LOGO )
(Logo: http://photos.prnewswire.com/prnh/20160401/350464LOGO )
(Photo: http://photos.prnewswire.com/prnh/20160401/350465 )

The extension of the initial cooperation, first started in 2011, extends benefits to all Kia vehicles owners and Kia dealers. The Kia networks will receive access to high-performance Total Quartz engine oils, specifically developed to optimize Kia engines’ performance, reliability and improve fuel economy benefits. Kia and Total will also develop joint marketing service programs aiming at increasing Kia dealers’ profitability, customer retention and customer satisfaction.

Through this partnership Kia and Total Lubrifiants confirm their shared aim of strengthening their growing presence in the global marketplace and combining their strengths in an “Alliance of Skills” to developing high-quality products and services for an unrivalled Kia Customer Service experience.

We are delighted to extend our global cooperation with Kia Motors Corp. This renewed Partnership confirms Totalsstrong commitment to accompany Kia Motors, in the long run, in its successful international expansion and to deliver innovative lubricants, recognized Total marketing expertise and dedicated aftermarket programs to Kia dealers and customers,” says Pierre Duhot, General Manager Automotive Division at Total Lubrifiants.

For the past 5 years, Total has demonstrated it has the worldwide coverage, strong marketing capabilities and high-quality lubricant technology to meet the needs of our Networks. Total will be a key partner for us in our global aftermarket strategy to enhance Kia customer and dealer satisfaction,” commented Steven Yoon, Vice President Overseas Service Division at Kia Motors Corp.

About Total

Total is a global integrated energy producer and provider, a leading international oil and gas company, and the worlds second-ranked solar energy operator with SunPower. Our 100,000 employees are committed to better energy that is safer, cleaner, more efficient, more innovative and accessible to as many people as possible. As a responsible corporate citizen, we focus on ensuring that our operations in more than 130 countries worldwide consistently deliver economic, social and environmental benefits.

http://www.lubricants.total.com

About Kia Motors

Kia Motors Corporation (http://www.kia.com) – a maker of quality vehicles for the young-at-heart was founded in 1944 and is Korea’s oldest manufacturer of motor vehicles. Over 3 million Kia vehicles a year are produced in 10 manufacturing and assembly operations in five countries which are then sold and serviced through a network of distributors and dealers covering around 180 countries. Kia today has over 50,000 employees worldwide and annual revenues of nearly US$44 billion. It is the major sponsor of the Australian Open and an official automotive partner of FIFA the governing body of the FIFA World Cup™. Kia Motors Corporation’s brand slogan “The Power to Surprise” represents the company’s global commitment to surprise the world by providing exciting and inspiring experiences that go beyond expectations.

For more information about Kia Motors and our products, please visit our Global Media Center at http://www.kianewscenter.com.

Source: Total

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April 5, 2016 at 3:38 pm

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New Survey Findings Reinforce the Need for Multi-sector Collaboration to Engage Consumers on Improving Diet and Lifestyle Choices

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— Survey explores how Forum for the Future and FrieslandCampina’s Food & Nutrition Report findings are contributing to accelerating progress on food and nutrition security in Southeast Asia

SINGAPORE /PRNewswire/ — A survey by FrieslandCampina, one of the world’s leading dairy companies, has found that the need for businesses, governments and civil society to engage and collaborate to secure the future of food and nutrition and educate consumers continues to grow in importance for representatives across the entire food value chain in Southeast Asia.

Leading the way - FrieslandCampina's partnership with Junior NBA promotes healthier eating and lifestyle choices
Leading the way – FrieslandCampina’s partnership with Junior NBA promotes healthier eating and lifestyle choices

The survey follows up on a report launched by Forum for the Future and FrieslandCampina, “Addressing food and nutrition security through partnerships and strong business leadership, in 2015. The Report was produced in consultation with representatives from the entire food value chain, including agri-food multinational companies, crop producers, financial institutions, retailers, academia, nutritionists, and international and non-governmental organisations. For the first time, non-traditional stakeholders such as logistics and packaging companies were also invited to participate in the conversation.

The survey enlisted all participants of the Roundtable to explore how the findings and recommendations of the Report are shaping their CSR strategies and accelerating progress on food and nutrition security in Southeast Asia.  The survey found that:

  • More than half of respondents consider collaboration between government bodies, NGOs and companies as the most important factor in engaging the consumer on better diet and lifestyle choices;
  • The Report has instigated more than a third of respondents to consider scaling up activities around agricultural sustainability and efforts to promote healthier eating and lifestyle choices;
  • 50% of respondents found the Report particularly insightful on new approaches to make sustainable changes to Supply Chain Infrastructure in order to benefit food and nutrition security in Southeast Asia; and
  • 50% of respondents believe that the collaborative opportunities flagged in the Report can be implemented within 2 – 4 years.

Whilst the challenge of sustainably feeding nine billion people by 2050 is high on the agenda of all participants, the growing double burden of malnutrition — undernutrition and overnutrition — was also highlighted as an important focus point for the survey respondents. It is a growing problem in Asia, costing the region 11% of its gross domestic product each year[1].

The survey highlighted the recognition amongst all actors that market-based approaches are important tools to achieve change on all accounts. One of the key goals of the Report was to find a good practical place to start and pursue a wider systems approach and the survey confirms that the food and agriculture industry is being proactive in its approach to accelerate change.

Based on the findings from the Roundtable, Forum for the Future has launched the Food Loss Consortium (FLC), which is a multi-stakeholder initiative designed to facilitate the progress towards real collaborative investments to improve the region’s grossly inefficient supply chains. The first step is to survey existing innovations in cold chain, ICT, packaging and supply chain structures that are commercially viable, scalable and have the potential to greatly reduce food losses; the Forum will then help business explore which innovations to pilot with their supply chain partners.

Since the publication of the Report, FrieslandCampina has sought to broaden the reach of its efforts to promote healthier eating and lifestyle choices amongst its consumers. The company has extended its agreement with the Jr NBA to encourage healthier lifestyle approaches amongst school-aged children across Southeast Asia as well as launching new product ranges specifically promoting good nutrition.

Piet Hilarides, Chief Operating Officer, FrieslandCampina Asia said: “The publication of our report addressing food and nutrition security in Southeast Asia has facilitated a number of interesting conversations throughout our value chain. We are focused on collaborating with our stakeholders to contribute to overcoming this pressing problem and are excited by the progress we are observing as a result of implementing a holistic approach. We did not expect change to happen immediately but are encouraged by the collective view of our survey respondents that the recommendations of our Report will instigate change in approaches to achieving food and nutrition security within the next two to four years.”

Ariel Muller, Director, Asia Pacific, Forum for the Future, said: “Bringing together a diverse body of stakeholders motivates businesses to reflect on their role in improving regional food security, and see opportunities to strengthen supply chain relationships by partnering to prepare for success in a resource-scarce future. We’re excited about the FLC because it allows us to use our expertise in cross-sector partnership to take this potential forward into real, collaborative action to build the food supply chains of the future.”

For more information, please contact:

Media Contacts

FrieslandCampina

Spurwing Communications

Ada Wong, Head of Public Affairs and Communications, Asia

Emma Thompson / Stephanie Tan

T: +65 6850 7931

T: +65 9107 5559

Email: Ada.wong@frieslandcampina.com

Email: FC@spurwingcomms.com

Notes to Editors

About the Report on Addressing food and nutrition security through partnerships and strong business leadership

In May 2015, FrieslandCampina and its partner, Forum for the Future, convened a roundtable comprising of 21 stakeholders from agri-food multinational companies, crop producers, retailers, financial institutions, logistics, packaging, academia, nutritionists, and international and non-governmental organisations in Singapore. Together, the group identified four key areas where businesses can and are already acting on food and nutrition security that can be scaled up:

  • Agricultural sustainability — Enabling sustainable production with improved land management, biodiversity conservation and strengthening the livelihoods of farmers.
  • Supply chain infrastructure — Identifying areas of waste, inefficiency, bottlenecks as well as opportunities to act through the entire food supply chain in the region.
  • Product innovation for nutrition — Ensuring the development of healthier products and improving access to more affordable staple and locally grown fresh produce.
  • Promoting healthier eating and lifestyle choices — Shifting consumer behaviour so that consumers can purchase healthier foods, live more active lifestyles and reduce food waste.

To further accelerate progress in these areas, the group offered three main recommendations for systems change on food and nutrition security:

  1. For businesses and groups of businesses working on smallholder agricultural sustainability to coordinate their efforts.
  2. For businesses in logistics, packaging and information and communications technologies (ICT) to work with those in the food supply chain to optimise efficiency and reduce waste.
  3. For companies, government bodies and NGOs to create a shared approach to engaging the consumer on better diet and lifestyle choices.

Roundtable participants

  1. Ishteyaque Amjad, Director, Corporate Affairs, APAC, Cargill
  2. Marjolijn Bragt-van Wijngaarden, Manager Nutrition & Clinical Trials Asia, FrieslandCampina
  3. Chris Davis, Director Partnerships and External Engagement, One Goal — Nutrition for Every Child
  4. Gwyneth Fries, Specialist in International Trade & Logistics, previously World Bank
  5. Dr. Stefan Germann, Executive Director, One Goal – Nutrition for Every Child
  6. Nazmul Islam, SMU graduate student (former communication and engagement manager, Food Industry Asia)
  7. Rebecca Lewis, Investment Analyst, Arisaig Partners
  8. Lloyd Lowe, Regional Lead, Packaging Industry Asia Pacific, BASF
  9. Grace Lin Kia, Manager, Corporate Communications, NTUC FairPrice Cooperative Ltd
  10. Benjamin McCarron, Founder, Asia Research and Engagement
  11. Dr. Chan Mei-Yen, Senior Lecturer, School of Agriculture, Food & Rural Development, Newcastle University
  12. Simone Muders, Research Manager RBP and Shared Value, Deutsche Post DHL
  13. Pitra Narendra, Manager, Government Relations and Policy, APAC, Cargill
  14. Hendro Harijogi Poedjono, Corporate Affairs Director, FrieslandCampina Asia
  15. Kavita Prakash-Mani, Executive Director, Grow Asia, World Economic Forum
  16. Raghavan Sampathkumar, Director – Stewardship with CropLife Asia
  17. Christopher Samuel, Director, Corporate Engagement, Monsanto Asia-Pacific
  18. Stephan Schablinski, Director DHL-SMU Green Transformation Lab, CEO, Green Freight Asia Network Ltd.
  19. Sasha Vasiljkovic, General Manager, Consumer & Strategic Accounts, Toll Global Logistics
  20. Ada Wong, Head of Public Affairs and Communications, FrieslandCampina Asia
  21. Thomas Zimmermann, Vice Director Regional Technical & Application Management, Human Nutrition Asia Pacific, BASF South East Asia Pte Ltd

About Royal FrieslandCampina

Every day Royal FrieslandCampina provides millions of consumers all over the world with food that is rich in valuable nutrients. With annual revenue of 11.3 billion euros, FrieslandCampina is one of the world’s five largest dairy companies, supplying consumer and professional products, as well as ingredients and half-finished products to manufacturers of infant & toddler nutrition, the food industry and the pharmaceutical sector around the world. FrieslandCampina has offices in 32 countries and almost 22,000 employees, and its products are available in more than 100 countries. The Company is fully owned by Zuivelcooperatie FrieslandCampina U.A, with 19,487 member dairy farmers in the Netherlands, Germany and Belgium — making it one of the world’s largest dairy cooperatives.

For more information please visit: www.frieslandcampina.com.

About FrieslandCampina Consumer Products Asia

FrieslandCampina’s Consumer Products Asia business group consists of operating companies that are active in the consumer products segment in Asia. FrieslandCampina has acquired excellent positions in many countries with strong brands and a wide range of products. These activities have a long and rich history. The export of dairy from Western Europe began back in the 1920s. The range of long shelf life products has expanded significantly: from milk powder, condensed milk, infant and children’s nutrition to dairy drinks, yoghurts and desserts. FrieslandCampina has operating companies in mainland China, Indonesia, Thailand, Vietnam, Myanmar, Malaysia, Singapore, Hong Kong and the Philippines. In Asia we market brands that have acquired strong positions. Dutch Lady is legendary in Malaysia andVietnam, Foremost is a leading brand in Thailand, Frisian Flag is widely known in Indonesia.

About Forum for the Future

Forum for the Future is a sustainability non-profit that works globally with business, government and others to solve complex challenges. We aim to transform the critical systems that we all depend on, such as food and energy, to make them fit for the challenges of the 21st century. We have 18 years’ experience inspiring new thinking, building creative partnerships and developing practical innovations to change our world. We share what we learn from our work so that others can become more sustainable.

Our mission is to create to a sustainable food system that gives everyone access to healthy, nutritious food whilst protecting and restoring the natural environment. We believe that sustainable nutrition is a hugely powerful guiding principle for accelerating overall progress on our food system challenges. We work to create change in the food system in three ways: by rethinking how value is created across food networks, by reconnecting people with their food, and by restoring resilience within the system. Through our partnerships and multi-stakeholder alliances we develop practical solutions to deliver the scale of change we need. Forum for the Future is a non-profit company limited by guarantee and registered in England and Wales.

Photo – http://photos.prnasia.com/prnh/20160331/8521602104

Source: FrieslandCampina

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April 5, 2016 at 3:23 pm

Posted in Uncategorized

Debtors Anonymous Offers Hope for People Struggling with Debt

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-Fellowship to celebrate 40th anniversary worldwide

NEEDHAM, Mass. /PRNewswire/ — Most people incur debt at various points in their lives. For some, unsecured debt—debt not secured by some form of collateral such as a house or car—becomes an addictive and unmanageable part of their lives. Debtors Anonymous (D.A.) offers hope for people whose use of unsecured debt causes problems and suffering in their lives and the lives of others.

Such debting can cripple and ruin someone’s life. For the compulsive debtor, debt is like alcohol for the alcoholic, food for the compulsive eater, and gambling for the compulsive gambler.

Based upon the Twelve-Step principles of Alcoholics Anonymous, the D.A. program has helped thousands find a new way of living that offers recovery from compulsive debting and hope for a healthier, happier, more prosperous life.

Forty years ago this April, a handful of debtors began meeting in New York City. Together, they found a solution to the pressures of compulsive debting. Since then, the Fellowship of D.A. has grown to some 500 registered meetings worldwide.

On April 15, 2016, members worldwide will celebrate the founding and growth of the Fellowship. Festivities will range from small group meetings and international phone meetings to large gatherings for hundreds of debtors.

About Debtors Anonymous

Debtors Anonymous is a non-profit organization whose members have a threefold purpose: to stop incurring unsecured debt, to share their experience with the newcomer, and to reach out to other debtors. Compulsive debting can also affect those who are self-employed or business owners. For them, Business Debtors Anonymous meetings are available to address their specific needs.

For more information about D.A. or to find out if there is a meeting in your area, visit the D.A. website atwww.debtorsanonymous.org, or call 1-781-453-2743.

Source: Debtors Anonymous

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April 5, 2016 at 3:19 pm

Posted in Uncategorized

Heart Media CEO Olivier Burlot Elected President of the Media Publishers Association Singapore

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SINGAPORE /PRNewswire/ — The Media Publishers Association Singapore (MPAS), now in its 10th Anniversary year, is delighted to announce that the Annual General Meeting was concluded successfully yesterday,March 31st 2016, at Singapore’s historic Ee Hoe Hean Club. Mr. Olivier Burlot, CEO of Heart Media, publishers of Men’s Folio, WOW (World of Watches), L’Officiel, Art Republik and Palace magazines, was elected president.

“With a 20 year experience in Asia and in the publishing world, it is for me a great honour to have been elected as the head of MPAS,” said Mr. Burlot. “The Association, more than ever, needed to gather all energies in the media world to face some highly disruptive challenges. I will ensure that, together with the members of the Executive Committee and Executive Director, we bring MPAS to greater heights and provide tangible benefits to its members.”

Mr. John Thet, publisher of Asian Geographic Magazines, publishers of ASIAN Geographic, Passport and Junior magazines, was elected Vice President. Mr. Alex Cano, publisher of Russian Singapore magazine, was reelected as Honorary Secretary. Ms. Rebecca Bisset, publisher of Expat Living’s stable of magazines was elected Honorary Treasurer.

Newly elected Executive Committee (EXCO) members are Mr. Timothy Charlton, publisher of Singapore Business Review, Healthcare Asia, Banking and Finance and Asian Power magazines; Mr. Michael Choo, publisher of caproasia.com; Mr. Eugene Lim, publisher of Wine & Dine magazine; Founding MPAS president Ho Sum Kwong, group publisher of Epicure, Hooked, Pets and Bites magazines.

The MPAS AGM was observed by Adrian Chue and Jovie Tan from the Media Development Authority.

The new officers and EXCO will all be working with Executive Director, Alexander Knight, to make MPAS’ 10th year memorable, as well as continuing to build on and create a vibrant community for Singapore’s media.

About MPAS

The Media Publishers Association Singapore was founded in 2006 as the Magazine Publishers Association Singapore to create a community for the various publishers in Singapore. The name was updated to reflect the changes in the industry and MPAS continues to thrive as it moves into it’s 10th anniversary year. For information on becoming a member or further information on the association please contact Alexander Knight at alex@mpas.org.sg.

Source: Media Publishers Association Singapore (MPAS)

Written by asiafreshnews

April 5, 2016 at 3:11 pm

Posted in Uncategorized

Victoza® (liraglutide 1.8 mg) Provided Superior HbA1c Reductions in Adults with Type 2 Diabetes Compared to Continued Sitagliptin Treatment

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BOSTON /PRNewswire/ —

For non-US medical media only.

For journalistic assessment and preparation before publication.

Abstract #689-P

Findings from a clinical trial comparing Victoza® (liraglutide 1.8 mg) and sitagliptin (100 mg), both in combination with metformin, demonstrated that switching from sitagliptin to Victoza® provided superior HbA1c reductions vs continuing with sitagliptin treatment in adults with type 2 diabetes. Results from the LIRA-SWITCH trial were presented at the Endocrine Society’s 98th Annual Meeting and Expo (ENDO 2016) in Boston, MA, US.[1]

The 26-week LIRA-SWITCH trial assessed the efficacy and safety of Victoza® as an add-on to metformin in 407 adults with type 2 diabetes who switched from sitagliptin.[1] Of the 407 adults uncontrolled on sitagliptin (HbA1c 7.5-9.5%) at week 26, those who switched to Victoza® (n=203) achieved a superior reduction in HbA1c vs those who continued their sitagliptin treatment (n=204) (−1.14% vs −0.54%; estimated treatment difference [ETD] −0.61%, 95% confidence interval [CI]: −0.82 to −0.40, p<0.0001).[1]

Additionally, adults who switched to Victoza® experienced significantly greater body weight reductions vs those who continued with their sitagliptin dose (−3.31 kg/−7.29 lb vs −1.64 kg/−3.62 lb; ETD −1.67 kg/−3.68 lb, 95% CI: −2.34 to −0.99, p<0.0001).[1]

“The LIRA-SWITCH trial results provide valuable insight that adults uncontrolled on sitagliptin may achieve a superior HbA1c reduction with liraglutide 1.8 mg vs continuing on sitagliptin treatment,” said Dr Maximo Maislos, Director of Western Negev Mobile Diabetes Clinic Program, and Diabetes and Metabolism, Ben-Gurion UniversityFOHS, Beer Sheva-Israel and investigator of the LIRA-SWITCH trial. “These findings are valuable as there is limited clinical evidence to guide treatment strategy when people with type 2 diabetes are uncontrolled on second-line therapy.”

The trial demonstrated that more adults with type 2 diabetes treated with Victoza® vs sitagliptin achieved HbA1ctargets <7% (50.6% vs 26.9%; OR [odds ratio]: 3.36; 95% CI: 2.08 to 5.42, p<0.0001) and ≤6.5% (29.5% vs 9.9%; OR: 5.44; 95% CI: 2.82 to 10.47, p<0.0001).[1] Furthermore, adults treated with Victoza® demonstrated significantly greater reductions in fasting plasma glucose vs those treated with sitagliptin (−1.84 vs −0.73; ETD: −1.10; 95% CI −1.50 to −0.71, p<0.0001).[1],[2]

Adverse events were more common in the Victoza® group vs the sitagliptin group (68.8% vs 56.9%), with gastrointestinal side effects more frequent with Victoza®: nausea (21.8% vs 7.8%) and diarrhoea (16.3% vs 9.3%).[1] There were no reports of severe hypoglycaemia and no reports of confirmed nocturnal hypoglycaemia.[1]

About the LIRA-SWITCH Trial

The 26-week trial was a randomised, double-blind, double-dummy, active-controlled trial involving 407 adults with type 2 diabetes not achieving adequate glycaemic control on sitagliptin as add-on to metformin.[1] Trial participants were previously treated with stable doses of sitagliptin (100 mg daily) and metformin (≥1500 mg daily or maximum tolerated dose ≥1000 mg daily) for ≥90 days.[1] Participants were randomised 1:1 to switch to Victoza® 1.8 mg or continue sitagliptin 100 mg, both in combination with metformin.[1]

About Victoza®

Victoza® (liraglutide) is a human glucagon-like peptide-1 (GLP-1) analogue with an amino acid sequence 97% similar to endogenous human GLP-1. Like natural GLP-1, Victoza® works by stimulating the beta-cells to release insulin and suppressing glucagon secretion from the alpha-cells only when blood sugar levels are high. Due to this glucose-dependent mechanism of action, Victoza® is associated with a low rate of hypoglycaemia.*[3] In addition, liraglutide reduces body weight and body fat mass through mechanisms involving reduced appetite and lowered energy intake.[3]

Victoza® was launched in the EU in 2009 and is commercially available in more than 80 countries, treating more than 1 million people with type 2 diabetes globally.[3],[4] In Europe, Victoza® is indicated for the treatment of adults with type 2 diabetes to achieve glycaemic control in combination with oral glucose-lowering medicinal products and/or basal insulin when these, together with diet and exercise, do not provide adequate glycaemic control.[3] In the US, Victoza® was approved in 2010 as an adjunct to diet and exercise to improve blood glucose control in adults with type 2 diabetes.[5]

*Hypoglycaemia has primarily been observed when Victoza® is combined with a sulfonylurea or basal insulin.

About Novo Nordisk

Novo Nordisk is a global healthcare company with more than 90 years of innovation and leadership in diabetes care. This heritage has given us experience and capabilities that also enable us to help people defeat other serious chronic conditions: haemophilia, growth disorders and obesity. Headquartered in Denmark, Novo Nordisk employs approximately 41,000 people in 75 countries and markets its products in more than 180 countries. For more information, visit novonordisk.com, Facebook, Twitter, LinkedIn, YouTube

Further information

Media:
Katrine Sperling
+45-4442-6718
krsp@novonordisk.com

Åsa Josefsson
+45-3079-7708
aajf@novonordisk.com

Investors:
Peter Hugreffe Ankersen
+45-3075-9085
phak@novonordisk.com

Daniel Bohsen
+45-3079-6376
dabo@novonordisk.com

Melanie Raouzeos
+45-3075-3479
mrz@novonordisk.com

Kasper Veje
+45-3079-8519
kpvj@novonordisk.com

References

  1. Bailey T, Takács R, Tinahones F, et al. Efficacy and safety of switching from sitagliptin to liraglutide in subjects with type 2 diabetes: a randomized, double-blind, double-dummy, active-controlled 26-week trial. Abstract number 689-P. Endocrine Society’s 98th Annual Meeting and Expo (ENDO 2016), Boston, MA, US; 1-4 April 2016.
  2. Data on file. Novo Nordisk. NCT01907854.
  3. EMA. Victoza® EU Summary of Product Characteristics. November 2015. Available at:http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/001026/WC500050017.pdf Lastaccessed 29.03.2016.
  4. Internal Calculations based on IMS Midas Quantum data. September 2015.
  5. FDA. Victoza® US prescribing information. Available at:http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022341s018lbl.pdf. Last accessed 29.03.2016.

 

Source: Novo Nordisk

Written by asiafreshnews

April 5, 2016 at 3:09 pm

Posted in Uncategorized

Semaglutide Demonstrated Superior Improvements In Glycaemic Control Vs Placebo In Adults With Type 2 Diabetes

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BOSTON /PRNewswire/ —

For non-US medical media only.

For journalistic assessment and preparation before publication.

Abstract #OR15-1

Findings from the first phase 3a clinical trial for semaglutide, an investigational glucagon-like peptide-1 (GLP-1) analogue, demonstrated that treatment with semaglutide administered once-weekly, significantly improved glycaemic control compared to placebo in adults with type 2 diabetes previously managed with diet and exercise alone. Results from the SUSTAIN 1 trial were presented today at the Endocrine Society’s 98th Annual Meeting and Expo (ENDO 2016) in Boston, MA, US.[1]

The 30-week SUSTAIN 1 trial, evaluating the efficacy and safety of semaglutide monotherapy vs placebo in 388 adults with type 2 diabetes,[1] showed that, from a mean baseline HbA1c of 8.1%, adults treated with 0.5 mg and 1.0 mg semaglutide achieved significantly greater HbA1c reductions of 1.5% and 1.6%, respectively, vs <0.1% with placebo.

In addition, more adults treated with 0.5 mg and 1.0 mg semaglutide achieved HbA1c targets compared with placebo: HbA1c <7% (74% and 72% vs 25%) and ≤6.5% (59% and 60% vs 13%). The trial also demonstrated that adults treated with 0.5 mg and 1.0 mg semaglutide achieved significantly greater reductions from baseline in mean body weight of 3.7 kg/8.16 lb and 4.5 kg/9.92 lb, respectively, vs 1.0 kg/2.20 lb with placebo.[1]

“Achieving glycaemic control remains a significant challenge for people with type 2 diabetes and their treating physicians,” said Christopher Sorli, SUSTAIN 1 investigator and Chair of the Department of Diabetes, Endocrinology and Metabolism, Billings Clinic, US. “It is encouraging that almost three out of four adults treated with semaglutide in the SUSTAIN 1 trial achieved the HbA1c target of less than seven percent.”

Furthermore, adults treated with both doses of semaglutide demonstrated significantly greater reductions from baseline in fasting plasma glucose compared with placebo (2.5 mmol/L or 45.2 mg/dL and 2.3 mmol/L or 42.1 mg/dL, respectively, vs 0.6 mmol/L or 9.9 mg/dL).[1]

The most common adverse events observed for adults treated with 0.5 mg and 1.0 mg semaglutide and placebo were gastrointestinal, which were mainly mild or moderate (nausea: 20.3% and 23.8% vs 7.8%; vomiting: 3.9% and 6.9% vs 1.6%; diarrhoea: 12.5% and 10.8% vs 2.3%). The rate of nausea diminished over time. Comparable rates of severe adverse events were observed for adults treated with 0.5 mg and 1.0 mg semaglutide compared with placebo (5.5% and 5.4% vs 3.9%). The proportion of adults discontinuing due to adverse events was low across treatment groups (6.3% and 5.4% vs 2.3%).[1]

About semaglutide

Semaglutide is an analogue of native human glucagon-like peptide-1 (GLP-1) that stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner, as well as decreases appetite and food intake.[2] Semaglutide administered subcutaneously once-weekly is in phase 3 development for the treatment of type 2 diabetes.

About SUSTAIN 1

SUSTAIN 1 is a randomised, double-blind, placebo-controlled, multicentre, multinational 30-week trial investigating the safety and efficacy of semaglutide, administered once-weekly, versus placebo in 388 people with type 2 diabetes who had not received any blood glucose lowering therapies 90 days prior to trial participation. The trial was conducted in Canada, Italy, Japan, Mexico, Russia, South Africa, UK and the US.

About the SUSTAIN clinical programme

SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) is a clinical programme for semaglutide, administered once-weekly, that comprises six phase 3a global clinical trials encompassing more than 7,000 people with type 2 diabetes as well as two Japanese trials encompassing around 1,000 people with type 2 diabetes.

About Novo Nordisk

Novo Nordisk is a global healthcare company with more than 90 years of innovation and leadership in diabetes care. This heritage has given us experience and capabilities that also enable us to help people defeat other serious chronic conditions: haemophilia, growth disorders and obesity. Headquartered in Denmark, Novo Nordisk employs approximately 41,000 people in 75 countries and markets its products in more than 180 countries. For more information, visit novonordisk.com, Facebook, Twitter, LinkedIn, YouTube

Further information

Media:
Katrine Sperling
+45-4442-6718
krsp@novonordisk.com

Åsa Josefsson
+45-3079-7708
aajf@novonordisk.com

Investors:
Peter Hugreffe Ankersen
+45-3075-9085
phak@novonordisk.com

Daniel Bohsen
+45-3079-6376
dabo@novonordisk.com

Melanie Raouzeos
+45-3075-3479
mrz@novonordisk.com

Kasper Veje
+45-3079-8519
kpvj@novonordisk.com

References

  1. Sorli C, Harashima S, Tsoukas G, et al. SUSTAIN 1: efficacy and safety of once-weekly semaglutide monotherapy versus placebo in subjects with type 2 diabetes. Abstract number OR15-1. Endocrine Society’s 98th Annual Meeting and Expo (ENDO 2016), Boston, MA, US; 1-4 April 2016.
  2. Nauck MA, Petrie JR, Sesti G, et al. A phase 2, randomized, dose-finding study of the novel once-weekly human GLP-1 analog, semaglutide, compared with placebo and open-label liraglutide in patients with type 2 diabetes. Diabetes Care. 2015; 39:231-241.

 

Source: Novo Nordisk

Written by asiafreshnews

April 5, 2016 at 3:00 pm

Posted in Uncategorized

Anbang-J.C. Flowers-Primavera Consortium Determines not to Proceed with Its Proposal to Acquire Starwood

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NEW YORK /PRNewswire/ — Anbang Insurance Group Co., Ltd., together with its partners J.C. Flowers & Co. and Primavera Capital Limited, (collectively, “the Consortium” ), today announced that the Consortium has determined not to proceed with its proposal to acquire Starwood Hotels & Resorts Worldwide, Inc. (NYSE: HOT) (“Starwood”).

The Consortium issued the following statement:

“We were attracted to the opportunity presented by Starwood because of its high-quality, leading global hotel brands, which met many of our acquisition criteria, including the ability to generate consistent, long-term returns over time.  However, due to various market considerations, the Consortium has determined not to proceed further.  We thank the Starwood Board, management team and its advisors for their efforts and support throughout this process.”

About Anbang Insurance Group

Anbang Insurance Group Co., Ltd. is a comprehensive insurance company, based in China, with a global network of over 35 million customers. Anbang’s business areas cover life insurance, property and casualty insurance, health insurance, pensions, banking and asset management. Anbang remains well positioned through the strength of our leading international franchises and their growth potential.  We look forward to continuing to execute on opportunities to meet our long-term value-driven strategic goals.

About J.C. Flowers & Co.

J.C. Flowers & Co. is a leading private investment firm dedicated to investing globally. Founded in 1998, J.C. Flowers & Co. includes, among others, a SEC registered investment adviser, J.C. Flowers & Co. LLC, that manages private equity funds, a broker dealer, J.C. Flowers Securities Co. LLC, that is SEC registered and a FINRA member and a fixed income asset management platform, J.C. Flowers Asset Management LLC.

About Primavera Capital Limited

Primavera Capital (“Primavera”) is a leading Asia-based investment firm. The firm employs a flexible strategy of growth capital and control-oriented investments and seeks to create long-term value by working closely with portfolio companies to improve operational efficiency, competitiveness, and earnings growth. Founded by Dr. Fred Hu, a renowned economist and successful investor, and a former partner and Chairman of Greater China at Goldman Sachs Group, the Primavera team combines global capital market experience, deep industry knowledge, and a strong network of relationships with policy-makers/regulators as well as leading CEOs and entrepreneurs inAsia and globally.

Contacts

Joele Frank / Andy Brimmer / Jonathan Keehner / Adam Pollack
Joele Frank, Wilkinson Brimmer Katcher
212-355-4449

Source:
Anbang Insurance Group Co., Ltd.
J.C. Flowers & Co.
Primavera Capital Limited

Related stocks: NYSE:HOT

Written by asiafreshnews

April 5, 2016 at 2:55 pm

Posted in Uncategorized