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Archive for May 25th, 2015

QT Vascular Announces First Patients Enrolled In Clinical Study Of Chocolate Touch(TM) PTCA Coronary Drug-Coated Balloon

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SINGAPORE, May 21, 2015 /PRNewswire/ —


Novel device addresses a very large coronary market globally
Study initiation represents achievement of key milestone ahead of time
No stents placement required in first 11 patients treated to date
Company is committed to build the clinical evidence needed to support approval and adoption

QT Vascular Ltd., together with its subsidiaries (“QT Vascular” or the “Group”), a global company engaged in the design, assembly and distribution of advanced therapeutic solutions for the minimally invasive treatment of vascular disease, today announced it has enrolled the first 11 patients in its First-In-Human (FIH) study of its novel Chocolate Touch™ PTCA (Coronary Drug Coated Chocolate®) in the Dominican Republic.

This study initiation represents achievement of key milestone ahead of time. Working closely with local and US physicians, QT Vascular has embarked on a potentially revolutionary study to evaluate the clinical utility of the Chocolate Touch™ PTCA for the treatment of de novo coronary lesions. If successful, this study would provide initial evidence of a new and unique device that could be able to treat the most common coronary disease in a way that minimizes the placement of stents in at least some lesion subsets. Stenting is currently the most commonly used treatment in coronary interventions, but it is a permanent implant that requires expensive long-term dual anti-platelet therapy and is associated with small but significant risks of fracture (1) and late-thrombosis (2)(3). The initial procedural outcomes with Chocolate Touch™ PTCA were successful in all 11 patients and importantly, no stent placement was required. There were also no cases with abrupt closure and no significant dissections were observed.

“I am pleased with the initial acute angiographic results of the Chocolate Touch™ PTCA; they look closer to a stent than a balloon. I have not observed any sub-acute occlusion in these patients which is one of the major risks with conventional balloons,” stated Dr. Jihad Mustapha of Metro Health Hospital, Wyoming, Michigan who performed some of the first cases.

Chocolate Touch™ PTCA is based on the unique Chocolate® balloon platform. By reducing acute trauma, Chocolate® was able to reduce severe dissections and thus reduce the need for unplanned stenting in the peripheral arteries when compared to conventional balloons (4). With the addition of the proven anti-proliferative drug, paclitaxel, Chocolate Touch™ PTCA offers the potential to achieve improved acute outcomes that will hold up over time due to paclitaxel’s ability to reduce the body’s response that may lead to the need for repeat interventions.

“I am pleased to offer to my patient this drug-coated balloon therapy that does not require a stent,” stated Dr. Carlos Garcia Lithgow of CECANOT Hospital in Santo Domingo, Dominican Republic. “In my country, the post-stent drug regimen is very expensive and many patients do not comply due to the high cost.”

“We have accelerated projects that we believe add strategic value to QT Vascular,” stated Eitan Konstantino, PhD, Chief Executive Officer of QT Vascular. “I am thrilled that the team has achieved this important milestone several months earlier than planned. We are looking forward to design and execute the clinical program required for both regulatory approvals and market acceptance.”

“The unique combination of low trauma and drug coating makes Chocolate® a promising treatment option. If the data show a low angiographic late loss, there is clearly a place for this device in the future interventional toolbox,” said world renowned Cardiologist, Professor Martin B. Leon, Director, Center for Interventional Vascular Therapy, Columbia University Medical Center / New York-Presbyterian Hospital.

While stents have been studied and used extensively for many years, it is desirable to minimize the use of permanent implants in the body. This approach has led to the development and increasing adoption of newer technologies such as bio-vascular scaffolds and drug-coated balloons. Chocolate Touch™ provides a new category consistent with how the market is trending towards less invasive therapies.


Andrew T.L. Ong, et al., Late Angiographic Stent Thrombosis (LAST) Events With Drug-Eluting Stents, J Am Coll Cardiol. 2005;45(12):2088-2092. doi:10.1016/j.jacc.2005.02.086


Chakravarty T, White AJ, Buch M, et al. Meta-analysis of incidence, clinical characteristics and implications of stent fracture. Am J Cardiol. 2010;106(8):1075-1080.


Mauri, et al., Twelve of 30 Months of Dual Anti-platelet Therapy After Drug Eluting Stents, NEJM, 4 Dec 2014, Vol. 371, No. 23, pp 2155-2166


Dr. Tony Das, et al. “Chocolate® BAR: Chocolate® PTA in a broad range of patients with PAD, a prospective post-marketing study”, LINC 2014

About QT Vascular
QT Vascular Ltd. (QT Vascular) is an emerging leader in the development and commercialization of next generation minimally invasive products for the treatment of complex vascular disease. The Company works closely with leading physicians and scientists from around the world to create differentiated devices that improve procedural and clinical outcomes. QT Vascular is based in Singapore with a US subsidiary, TriReme Medical LLC, in Pleasanton, California. The Company was listed on the Catalist Board of the Singapore Exchange Securities Trading Limited on 29 April 2014.

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Source: QT Vascular Ltd.

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May 25, 2015 at 11:37 pm

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Martell Cognac Celebrates 300th Anniversary with Spectacular Party at the Palace of Versailles

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PARIS, May 21, 2015 /PRNewswire/ — Martell, the oldest of the great cognac Houses celebrated its landmark 300th anniversary at a glittering celebration which took place last night at the historic Palace of Versailles in France.

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300 VIP guests from more than 15 countries attended the spectacular evening, including Martell’s Ambassador and Guest of Honour at the event, the internationally-acclaimed actress Diane Kruger. Other guests included Solange Knowles, Olivia Palermo, Naomie Harris and Antoine Firino Martell, one of the descendants of the House’s Founder Jean Martell, as well as Hong Kong actress and singer-songwriter Karen Mok, guest of honour from Asia, who all enjoyed an incredible evening where Martell’s 300 year history was transformed into a vibrant and festive celebration with every moment turned into an extraordinary pleasure.

After a private tour of the Palace, guests experienced an exclusive fly past over Versailles by the Patrouille de France and an exclusive preview of an experiential exhibition representing each stage of Martell’s unique cognac expertise. After tasting cocktails created especially for the House’s Tricentenaire, all 300 guests took their seats for a fully immersive gastronomic experience designed around Jean Martell’s original journey to Cognac, created exclusively for Martell by the world-renowned, innovative French chef, Paul Pairet.

Diane Kruger commented: “Tonight we brought the modern spirit of French Art de Vivre to life to celebrate Martell Cognac’s 300th anniversary. It’s not often that you get to attend such a spectacular event at such an iconic location and it has been a privilege to be a part of the celebrations this evening. The Palace of Versailles – considered by many to be the ‘birthplace’ of Art de Vivre – provided a spectacular setting to celebrate 300 years of Martell and I hope all the guests got to discover a little bit of the French way of living for themselves this evening.”

Philippe Guettat, CEO and Chairman of Martell added: “Tonight was all about celebrating the momentous anniversary of the Martell House and looking forward to the next 300 years. This has been an exceptional opportunity for us to gather guests from so many countries at the iconic Palace of Versailles to celebrate the Martell House’s 300 year history. This is surely a pinnacle moment for the House and we hope to keep building on our success as we look forward to Martell’s future.”

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Source: Martell

Written by asiafreshnews

May 25, 2015 at 11:11 pm

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Herman van Rompuy: “There Must be Results, That’s Where the Challenge is”

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BRUSSELS, May 21, 2015 /PRNewswire/ —

Herman van Rompuy was President of the European Council until November 2014. The first President of Europe reflects on five turbulent years and looks ahead to Europe’s future. “When I began my work I did not know what colossal challenges I would face.”

“Essentially, my method of working was no different than that of the leader of a country, a state or even a company. I also had to listen, gain people’s trust and propose creative solutions.” These are the words of Herman van Rompuy, former President of the European Commission of Heads of State and Government (2009-2014). “Except that more is demanded of you. The stakes are often quite high. In the EU, resolutions can only be made unanimously with 28 member states. As the President, you therefore must ensure that all member states can see eye to eye.”

Difficult times

Van Rompuy recalls two moments when he feared that the Eurozone would meet an unfortunate end. “Europe was under extreme pressure in the autumn of 2011. A political crisis broke out in Greece and the problems in Italy, the third largest economy in Europe, were also intensifying. That led to the resignation of the Greek Prime Minister and of the Italian Prime Minister, Berlusconi. That was a difficult period. The EU came under heavy criticism not just internally but also externally, from the rest of the world. The stakes were high. Because if the Eurozone were to collapse then the global economy would also be at risk. That simply had to be prevented.”

Still work to be done

Van Rompuy does not have much advice to offer Donald Tusk, his Polish successor. “I am not the sort of person who suddenly discovers all sorts of new things about Europe. During my presidency we always tried to do the right thing. I have confidence that my successor will do what has to be done and will do so responsibly. We are dealing with high unemployment, a low level of competitiveness, a difficult financial recovery and consumer confidence that is only slowly getting off the ground… We need growth and jobs. There must be results, and that’s where the challenge is. If we do not achieve that then Europe’s political stability is in danger.”
Source: Assemblee Speakers Bureau

Written by asiafreshnews

May 25, 2015 at 10:32 am

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